Noteworthy Facts About Telomeres
These days, there are various reasons why testing using telomerase analysis technology (TAT) is becoming popular. Essentially, this test serves as a biomarker to determine the early prognosis and risk of certain diseases like cancer. The telomere length is the focus of this process, incorporating the careful evaluation and analysis of it. The length of telomeres is a key factor in determining age-related diseases. Telomeres may be used as an individual biomarker or in combination with other biomarkers. Telomeres are very convenient biomarkers because you can get them from various body samples. Understanding telomeres helps a lot for those who are planning to make use of telomerase analysis technology. For some noteworthy facts about telomeres, find out here and get info.
As previously stated, there is a link between the length of your telomeres and age-related health conditions. Getting older is a normal part of life. To this day, many scientists are still puzzled over why people age and what causes aging. You can find plenty of theories about aging like oxidative stress damaging one’s DNA. Can you also put the blame on glucose? What about the cells of the body just all along following a biological timetable that is pre-programmed? While there are many theories, one thing is for sure: there are many causes of aging.
If you look at one theory that resonates a lot, it would have to be that telomeres are associated with the aging process. Telomeres are tiny protective caps that you can find at ends of DNA molecules that form your chromosomes. Their main role is to ensure that the ends of your chromosomes don’t end up sticking to each other or fraying.
Telomeres also play a crucial role in ensuring that a person’s DNA is properly copied when cells divide. Sadly, in the process of DNA replication, there are instances where a few of the DNA building blocks or nucleotides found at the end of the strand are not copied into the new DNA. The outcome will be a loss of some crucial genetic information. As cells divide regularly, you can expect these DNA strands to shorten.
After all the process of cell division, why is it still possible to have any DNA left? To answer this question, you have to take a look at how telomeres work. Telomeres comprise the same DNA sequence repeated time and time again, making them somehow disposable. They play a role in ensuring that the rest of the DNA does not get damaged. As they get shorter over time, they will not be losing any crucial genetic information.
Cells age when telomeres shorten as well as other factors. By the time your telomeres get too short, your cells will not be able to divide as effectively. After reaching a critical point, these cells become inactive that lead them to die or either accumulate damage they cannot repair.